Clinical AspectsCervical spondylosis refers to a degenerative process of the cervical spine producing narrowing of the spinal canal and neural foramina, producing compression of the spinal cord and nerve roots, respectively. Through wear and tear with aging, the following processes occur:
Myelopathy refers to dysfunction of the long tracts of the spinal cord. It may manifest as weakness and spasticity, sensory loss, position sense loss, and incontinence. Myelopathy develops in only 5-10% of patients with symptomatic spondylosis. Interestingly, coexistent neck and radicular pain are unusual.
Several syndromes of cervical spondylotic myelopathy have been delineated (Gregorius):
Radiographic EvaluationPlain X-rays of the cervical spine disclose osteophytes at the involved level, loss of disc height, and often a narrow spinal canal. It must be emphasized that some degree of spondylotic changes are seen in 25-50% of the population over the age of 50 years, and in 75% of people over 75 years! Obviously, most people do not develop symptoms from these processes; a patient's clinical picture must be assessed carefully to determine which symptoms may be caused by spondylosis, and to what degree. This must be individualized for each patient.
Myelogram with CT, as discussed previously, provides the best bony detail. In most cases MRI may be unnecessary.
TreatmentUnlike the case with cervical disc herniation, most patients do not improve with nonoperative treatment, because of the progressive degenerative nature of spondylotic disease. Patients who are poor medical candidates or for another reason are treated nonoperatively must be followed closely for worsening of myelopathy.
The surgical options are anterior or posterior decompression. Anterior approaches are similar to that described for herniated cervical disc and may be performed at multiple levels as appropriate. Alternatively, the entire vertebral body may be removed (corpectomy) between adjacent levels of spondylosis, or several bodies may be removed. A bony graft is placed for fusion. With long grafts, a plate and screws are usually placed. Posterior decompression involves laminectomy at the affected levels. The effectiveness of posterior decompression is contoversial, but most surgeons today would probably prefer an anterior procedure when feasible.
OutcomeOverall, improvement following anterior decompression with interbody fusion is seen in 60-84% of patients. When myelopathy alone was present, 40% improved in one study. When myelopathy and radiculopathy were both present, the myelopathy was improved in 60% and completely relieved in another 12%.
Several factors have been shown to impact negatively on the degreee of improvement from surgery:
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Last modified January 27, 1996
A Patients Guide to Degenerative
Editor's Note: This is an excellent basic overview of cervical spondylosis. However, it should be noted that the treatment and diagnostic tests may vary among health care providers.
The cervical spine consists of the top 7 vertebrae of the spine. Doctors often refer to these vertebrae as C1 - C7, with the "C" indicating cervical, and the numbers 1-7 indicating the level of the vertebrae. C1 is closest to the skull, while C7 is closest to the thoracic (chest/rib cage) region of the spine.
The cervical spine is particularly susceptible to degenerative problems because of:
For example, cervical motion segments (i.e. a disc with a vertebra above and below) consist of five "joints" (the intervertebral disc, the two facet joints, and the two uncovertebral joints).
There are several symptoms that may indicate the presence of a degenerative condition in the cervical spine. Symptoms include, neck pain, pain around the back of the shoulder blades, arm complaints (pain, numbness or weakness), and rarely, difficulty with hand dexterity or walking.
The degenerative process may begin in any of the joints in the cervical spine, and over time it may also cause secondary changes in the other joints. For example, an intervertebral disc may be primarily affected. As the disc narrows, the normal movement of that segment is altered, and the adjacent joints (also called ‘osteoarthritis’ or ‘degenerative joint disease’) are subjected to abnormal forces and pressures leading to degenerative arthritis (i.e. inflammation of a joint).
Neck pain as a result of spondylosis (i.e. a degenerative change) is relatively common. The pain may radiate, or spread, into the shoulder blade or down the arm. Patients may have an arm complaint (such as pain or weakness), as the result of nerve root compression from a bone spur.
Dysphagia (i.e. difficulty in swallowing) can result from large anterior osteophytes (i.e. bony growths at the front of the spine), although this is rare.
Diagnosing the Problem
When a patient with a degenerative disorder of the cervical spine is examined by a doctor, one or more symptoms are likely to be apparent. The doctor will ask the patient many questions to gain a detailed history of the condition. A thorough evaluation of the patient will be conducted, including several types of tests, so as to accurately identify the problem.
A neurologic examination will be done to rule out a neurologic deficit. A shoulder examination will also probably be done to ensure that the symptoms are indeed originating from the neck.
Various diagnostic tools may be used, including:
X-rays are useful for identifying such problems as:
Computed tomography (CT) can highlight the bony changes associated with degenerative spondylosis (arthritis). Osteophytes can be observed and evaluated as well. However, CT does not provide for optimal evaluation of discs (although it may sometimes show disc herniations).
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a powerful tool in the assessment of patients with cervical spondylosis. Images from MRI's can help doctors to identify disc herniations, osteophytes and joint arthrosis. MRI is best suited for soft disc herniations, but often times more information is needed.
This is the "gold standard". It is often utilized in complex cases involving multi-level disease, or suboptimal MRI images. It is very useful in delineating bone spurs from safe disc herniations.
As in the lumbar and thoracic spine, cervical discography (see figure) remains controversial. Although the discogram may add to the clinician's knowledge, it should not be used by itself to predicate treatment.
Facet blocks in the cervical spine are subject to the same criticisms as facet blocks used elsewhere. There is little scientific documentation to validate their use. Repeating the test and comparing results at different levels probably gives much more useful information than carrying out facet blocks at one or more levels at one point in time. The do aid physicians in determining the "pain generator".
After the doctor has conducted the necessary tests to identify the problem in the cervical spine, a treatment plan will then be developed. Various treatment options are available, and can be subdivided into two categories:
Nonoperative treatment of cervical degenerative disease provides good to excellent results in over 75% of patients. A multidisciplinary approach includes:
A surgeon is likely to consider a surgical treatment of a cervical degenerative problem if one or more of the following criteria are met:
The surgical procedure proposed for these patients is removing the bone spur and possible fusion of two or more cervical vertebrae. In most instances, the preferred approach is an anterior (i.e. from the front) interbody fusion. Using the anterior approach, a surgeon can perform a complete discectomy (i.e. removal of the disc between two vertebrae), and then seek to restore the normal disc space height and normal lordosis (i.e. the concave curve in the cervical spine) by implanting a carefully sculpted graft. A titanium plate may be utilized to improve the rate of fusion and avoid a neck brace.
A posterior approach (from the back of the spine) is often considered when a cervical disc has herniated laterally (i.e. sideways).
Cervical spine degenerative disorders can be diagnosed more accurately and treated more effectively today than even five or ten years ago. Under the guidance and treatment of an expert medical team, most patients can now hope to see a very significant improvement in their condition.
Cervical Stenosis & Myelopathy
What is It? What Treatments Are Available?
What are Cervical Stenosis & Myelopathy?
The cervical spine (neck) is made up of a series of connected bones called vertebrae. The bones protect the spinal canal that runs through the vertebrae and carries the spinal cord. The spinal cord contains nerves that give strength and sensation to the arms and legs, and provide bowel and bladder control. Numerous connections (discs, joints, ligaments and muscles) between the cervical vertebrae provide support, stability and allow motion.
With age, intervertebral discs become less spongy and lose water content. This can lead to reduced disc height and bulging of the hardened disc into the spinal canal. The bones and ligaments of the spinal joints thicken and enlarge, also pushing into the spinal canal. These changes are common after age 50 and are generally called cervical spondylosis or cervical stenosis.
Cervical stenosis may occur at a very slow or very fast rate. These changes cause narrowing of the spinal canal and can pinch the spinal cord and nerve roots. Spinal cord or nerve function may be affected, causing symptoms of cervical radiculopathy or myelopathy. (Cervical stenosis is the name for the actual narrowing of the canal, while cervical myelopathy indicates injury to the spinal cord and its function.)
What are the Symptoms?
Stenosis does not necessarily cause symptoms; if symptoms do appear, they usually indicate the presence of radiculopathy or myelopathy.
About half of patients with cervical myelopathy have pain in their neck or arms; most have symptoms of arm and leg dysfunction. Arm symptoms may include weakness, stiffness or clumsiness in the hands, such as being unable to button a shirt, turn a doorknob or open a jar. Leg symptoms may include weakness, difficulty walking, frequent falls or the need to use a cane or walker as the disease progresses.
Urinary urgency is also common. In late cases, bladder and bowel incontinence can occur.
Symptom progression may also vary. You may:
The first signs are often increased knee and ankle reflexes. These may only be detected in a neurologic exam. Early detection is important to determine treatment which may help slow symptom progression.
How is It Diagnosed?
Your doctor will begin by asking you questions and performing a physical examination,
and may order tests. In addition to the symptoms you describe to
your doctor, a physical examination may reveal other findings such
Other findings include rapid foot beating triggered by turning
the ankle upward (clonus), extension of the big toe when the foot
is stroked (Babinskis sign), contraction of the thumb and
index finger after flipping of the middle finger (Hoffmans
sign). One or several of these findings may lead your doctor to
suspect spinal cord dysfunction. Range of motion or flexibility
of the neck often decrease with age and does not necessarily indicate
nerve or spinal cord dysfunction.
Cervical spine X-rays may not provide enough information to confirm cervical stenosis, but may rule out other conditions. Magnetic resonance imaging (MRI) is often used. MRI images are very detailed and show the tight spinal canal and pinching of the spinal cord. Cervical stenosis (narrowing of the spinal canal) and myelopathy can occur at one level or many levels of the spine and MRI is useful for looking at several levels at one time. A computed tomography (CT) scan may give clearer information about bony invasion of the canal and can be combined with an injection of dye into the fluid around the spinal cord and nerves (myelography).
Electrical studies assess or distinguish between myelopathy and other conditions. Electromyography (EMG) and nerve conduction velocity (NCV) may help rule out peripheral nerve problems such as a pinched nerve in your neck or arm that can cause symptoms like those of myelopathy. Somatosensory Evoked Potentials (SSEP) testing is done by stimulating the arms and/or legs and reading a signal in the brain. A delay in the length of time it takes the signal to reach the brain can indicate spinal cord compromise. This study may also rule out other disorders that may be confused with myelopathy.
What Treatments Are Available?
In mild cases of cervical stenosis with or without myelopathy, nonoperative treatment may be suitable. However, in cases with increasing weakness, pain or the inability to walk, surgical treatment is usually recommended. Surgical options include anterior decompression and fusion, where the disc and bone material causing spinal cord compression is removed from the front and the spine is stabilized. The stabilizing of the spine, called a fusion, places a bone graft (implant) between cervical segments to support the spine and compensate for the bone and discs that have been removed. Often, your surgeon may choose to add a small metallic plate and screw fixation device for even more strength.
Another surgical option, laminectomy, involves surgery from the back of the neck. Laminectomy is a procedure where the bone and ligaments pressing on the spinal cord are removed. In some cases, your surgeon might add a fusion to stabilize the spine as well. A second option, called laminaplasty, involves expanding the spinal canal. In this procedure, part of the bony arch is removed and a hinge created. This hinge is opened to increase the room for the spinal cord.
Medication and Pain Management
Medications used to treat cervical myelopathy reduce pain, muscle spasm or other symptoms. Your doctor may prescribe one or several types of medication to decrease your discomfort and increase function. However, you should take the medication only as directed and needed. Taking more will not help you recover faster, might cause unwanted side effects (such as constipation and drowsiness) and can result in addiction. Make sure your doctor knows about all medications you are taking (even over-the-counter, natural, herbal or alternative medications) and any allergies or other problems you have had with medications in the past (including any history of substance abuse). All medications have risks and benefits that you should review with your doctor. A physician should monitor long-term use of any medication.
Medications used to control pain are called analgesics. Many do not require a prescription. However, if you have severe persistent pain, your doctor might prescribe higher doses of non-steroidal anti-inflammatory drugs (NSAIDs) or muscle relaxers. For even more severe pain, he/she may prescribe stronger narcotics (opioids).
NSAIDs are analgesics that also reduce swelling and inflammation. NSAIDs include aspirin, ibuprofen, naproxen and a variety of prescription drugs. If your doctor prescribes anti-inflammatory medications you should watch for side effects like stomach upset or bleeding. (For more information about the proper use of nonsteroidal anti-inflammatory drugs, see the NASS patient education brochure on NSAIDs.)
Corticosteroids are very powerful anti-inflammatory medications taken either orally or by injection for pain relief. These medications are associated with more side effects, especially when taken for a long time.
Epidural steroid injections may be recommended if your doctor feels they are appropriate. These are injections of corticosteroids into the epidural space (the area around the spinal cord) performed by a physician with special training in this technique. The purpose of the injection is to reduce inflammation and may be used in conjunction with a rehabilitation program. An initial injection may be followed by others depending on your response.
Your doctor may prescribe antidepressants, antiseizure or other medications that are known to help painful conditions. These work by decreasing symptoms through different mechanisms than analgesic medications.
Other pain management strategies may also be used. Trigger point injections place local anesthetics (sometimes combined with corticosteroids) directly into painful soft tissue or muscles. Facet joint injections also may be used. Your doctor may also prescribe ice or heat for the painful area. These may be done as part of a complete rehabilitation and treatment program.
Nonoperative treatment of cervical stenosis with or without myelopathy is aimed at reducing pain and increasing function. Nonoperative treatments do not change the spinal canal narrowing, but may provide long-lasting pain control and improved life function without surgery. A comprehensive rehabilitation program may require 3 or more months of supervised treatment.
People with cervical myelopathy symptoms frequently avoid activity. Decreased activity reduces flexibility, strength and cardiovascular endurance. A physical therapy or exercise program usually begins with stretching exercises to restore flexibility to tight muscles in the neck, trunk, arms and legs. You may be asked to stretch frequently to preserve flexibility. Cardiovascular exercises for arms and legs (arms and/or leg cycle, treadmill, swimming) may be added to build endurance and improve circulation. Improved blood supply may ease some of the symptoms of myelopathy. You may also be given specific strengthening exercises for arm, leg and trunk muscles. Your therapist may work with you on everyday activities such as changing positions from sitting to standing, standing to sitting and getting out of bed.
Everyday activities will be easier if flexibility, strength and
endurance are maintained and increased. Your physical therapist
and doctor can tell you how to add a continuing exercise program
into your life, either at home using simple equipment or at a fitness
What If I Need Surgery?
Your doctor may recommend surgery if you fail to respond to nonoperative treatment. Surgery may be done from the front of the neck (anterior) or from the back of the neck (posterior). It will always involve removing pressure from the spinal cord and spinal nerves (decompression) and will generally involve some form of stabilization (fusion) of the affected areas. Your doctor may recommend metal implants (instrumentation) as an accessory to the surgery to support the vertebrae while they heal and fuse together. Occasionally, a combined or anterior/posterior approach may be necessary. After surgery, your doctor may recommend the use of a brace, ranging from a soft collar up to a halo-vest, depending upon the surgical procedure.
Several factors are considered by your doctor when choosing your surgical procedure. Typically, these include the alignment of your spine, location of the compression (front or back), quality of your bone, number of levels involved and your overall medical status. Based on these factors, your doctor may recommend anterior, posterior or combined approaches.
Anterior surgery is performed through the front of the neck. Two similar but separate procedures may be recommended. The first is an anterior cervical discectomy and fusion. This may be done at one or more levels. This procedure removes the disc and bone spurs pinching the spinal cord and spinal nerves. The disc is replaced with an implant to fuse and support the spine. If more than one level of the spine is involved, your doctor may recommend a corpectomy and strut graft. This procedure removes the disc above and below the vertebra and the intervening vertebra to completely remove pressure from the spinal cord. The bone is replaced with a strut graft to stabilize the spine.
Posterior surgery is performed through the back of the neck. Two common operations are laminectomy and laminaplasty. These operations are very similar in that they both remove pressure from the spinal cord and spinal nerves. In laminectomy, the rear elements of the vertebra, also known as the lamina, are removed. In laminaplasty, part of the bony arch is removed and a hinge created. This hinge is opened to make the room for the spinal cord.
After surgery, you will remain in the hospital for at least a few days. Most patients are able to return to all activities within 6 to 9 months. A postoperative rehabilitation program is usually prescribed to guide return to activities and normal life. (For more information, see the NASS patient education brochure on Spinal Fusion Surgery.)
Disclaimer: This information is for general information and understanding only and is not intended to represent official policy of the North American Spine Society. Please consult your physician for specific information about your condition.
Copies of this information in a glossy color brochure are available from the NASS Office by calling toll-free 1-877-SpineDr.
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